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Portfolio (Quarterly) Guide ↗

RTW INVESTMENTS, LP

· CIK 0001493215
13F Portfolio $10.0B AUM 88 positions Filed May 15, 2026 EDGAR ↗ ← All Funds
Q1 2026 Q4 2025 · All 9 New 25 Added 12 Reduced 12 Exited
Page 3 of 5  ·  88 positions
# Ticker Company Sector Shares Value ↓ % Port Chg Shares Chg % Period Price ① Since Period ①
41 ALKS ALKERMES PLC Healthcare 1,672,356.0 $59.1M 0.59% $35.36 +6.0%
42 CMPS COMPASS PATHWAYS PLC Healthcare 10,632,390.0 $58.8M 0.58% +1.9M +21.4% $5.53 +87.5%
43 KOD KODIAK SCIENCES INC Healthcare 1,487,934.0 $56.7M 0.56% $38.12 +1.5%
44 REPL REPLIMUNE GROUP INC Healthcare 7,356,916.0 $56.3M 0.56% +217K +3.0% $7.65 -35.6%
45 CRNX CRINETICS PHARMACEUTICALS IN Healthcare 1,451,326.0 $52.7M 0.53% +100K +7.4% $36.32 +5.5%
46 QURE UNIQURE NV Healthcare 2,586,356.0 $42.3M 0.42% -1.1M -30.3% $16.35 +69.7%
47 WAY WAYSTAR HLDG CORP Technology 1,630,000.0 $39.3M 0.39% NEW $24.11 -21.9%
48 ARWR ARROWHEAD PHARMACEUTICALS IN Healthcare 585,682.0 $36.7M 0.36% $62.70 +22.3%
49 OBIO ORCHESTRA BIOMED HLDGS INC Healthcare 8,306,063.0 $35.3M 0.35% $4.25 -3.3%
50 VERASTEM INC 6,576,306.0 $34.9M 0.35% $5.30
51 EVMN EVOMMUNE INC Healthcare 1,502,235.0 $34.5M 0.34% +219K +17.0% $22.99 -1.2%
52 SYK STRYKER CORPORATION Healthcare 100,000.0 $32.9M 0.33% -145K -59.2% $328.59 -7.0%
53 SVRA SAVARA INC Healthcare 5,952,380.0 $32.5M 0.32% $5.46 -3.5%
54 CADL CANDEL THERAPEUTICS INC Healthcare 6,422,018.0 $31.5M 0.31% NEW $4.90 +79.0%
55 AQST AQUESTIVE THERAPEUTICS INC Healthcare 7,426,471.0 $30.8M 0.31% +1.2M +18.8% $4.15 +0.5%
56 AKTS AKTIS ONCOLOGY INC Healthcare 1,592,043.0 $28.5M 0.28% NEW $17.89 +9.3%
57 NGNE NEUROGENE INC Healthcare 1,362,456.0 $27.5M 0.27% $20.16 +55.1%
58 CGEM CULLINAN THERAPEUTICS INC Healthcare 1,705,960.0 $24.2M 0.24% $14.21 +10.7%
59 CMPX COMPASS THERAPEUTICS INC Healthcare 4,186,599.0 $22.1M 0.22% +1.7M +67.5% $5.29 -64.8%
60 DNTH DIANTHUS THERAPEUTICS INC Healthcare 248,063.0 $20.8M 0.21% NEW $83.92 +1.7%
Page 3 of 5  ·  88 positions

Period Price is the implied market price on the last day of the reporting period, calculated as reported value ÷ shares held. It is not the fund's purchase price or cost basis — the fund may have initiated or added to the position at any point during the quarter at a different price. Since Period shows the price change from that quarter-end snapshot to today's last price — it reflects stock movement after the report date, not the fund's actual return.

Sector Allocation
Healthcare 99.6%
Technology 0.4%