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Portfolio (Quarterly) Guide ↗

RTW INVESTMENTS, LP

· CIK 0001493215
13F Portfolio $10.0B AUM 88 positions Filed May 15, 2026 EDGAR ↗ ← All Funds
Q1 2026 Q4 2025 · All 9 New 25 Added 12 Reduced 12 Exited
# Ticker Company Sector Shares Value ↓ % Port Chg Shares Chg % Period Price ① Since Period ①
1 NTRA NATERA INC Healthcare 1,250,000.0 $250.0M 2.49% -250K -16.7% $199.99 -1.5%
2 COGT COGENT BIOSCIENCES INC Healthcare 5,458,675.0 $210.1M 2.09% -2.1M -28.1% $38.49 -11.2%
3 APLS APELLIS PHARMACEUTICALS INC Healthcare 3,685,045.0 $148.2M 1.48% -4.0M -51.9% $40.23 +2.0%
4 ZLAB ZAI LAB LTD Healthcare 6,574,032.0 $123.7M 1.23% -385K -5.5% $18.81 +8.1%
5 TSHA TAYSHA GENE THERAPIES INC Healthcare 13,680,248.0 $61.2M 0.61% -2.7M -16.6% $4.47 +40.9%
6 QURE UNIQURE NV Healthcare 2,586,356.0 $42.3M 0.42% -1.1M -30.3% $16.35 +69.7%
7 SYK STRYKER CORPORATION Healthcare 100,000.0 $32.9M 0.33% -145K -59.2% $328.59 -7.0%
8 BBNX BETA BIONICS INC Healthcare 2,000,000.0 $20.0M 0.20% -500K -20.0% $10.02 -5.6%
9 JBIO JADE BIOSCIENCES INC Healthcare 573,205.0 $8.1M 0.08% -876K -60.5% $14.05 +71.7%
10 LRMR LARIMAR THERAPEUTICS INC Healthcare 1,500,000.0 $6.8M 0.07% -1.6M -52.0% $4.50 -13.6%
11 TENAX THERAPEUTICS INC 370,246.0 $5.9M 0.06% -8K -2.1% $15.99
12 XGN EXAGEN INC Healthcare 395,231.0 $1.2M 0.01% -395K -50.0% $3.00 +21.3%

Period Price is the implied market price on the last day of the reporting period, calculated as reported value ÷ shares held. It is not the fund's purchase price or cost basis — the fund may have initiated or added to the position at any point during the quarter at a different price. Since Period shows the price change from that quarter-end snapshot to today's last price — it reflects stock movement after the report date, not the fund's actual return.

Sector Allocation
Healthcare 99.6%
Technology 0.4%