SION

Sionna Therapeutics, Inc. NASDAQ Listed Feb 7, 2025

Healthcare ·Biotechnology ·US · sionnatx.com

$43.24

Mkt Cap $1.9B

52w Low $11.77 90.7% of range 52w High $46.46

50d MA $38.47 200d MA $34.42

P/E (TTM) -20.8x

EV/EBITDA -18.0x

P/B 5.1x

Debt/Equity 0.0x

ROE -24.5%

P/FCF -24.7x

RSI (14) —

ATR (14) —

Beta 3.01

50d MA $38.47

200d MA $34.42

Avg Volume 356.8K

Sionna Therapeutics, Inc. is a biopharmaceutical company. The Company provides treatment paradigm for cystic fibrosis patients by developing medicines that normalize the function of the cystic fibrosis transmembrane conductance regulator.

CIK (SEC)

2036042

Phone

617 819 2020

21 Hickory Drive Suite 500 · Waltham, MA 02451 · US

Date	Time	Est	Rptd	Surp	Base	Gap%	D1%	D2%	D3%	D4%	D5%	Guide ▲★
May 8, 2026	BMO	—	—	—	43.31	+1.4%	+2.1%	—	—	—	—	—
May 7, 2026	BMO	—	—	—	43.29	+0.1%	+0.0%	—	—	—	—	—
Mar 2, 2026	BMO	-0.54	-0.46	+14.7%	33.92	+0.0%	+0.5%	+0.5%	+1.9%	+1.9%	+5.9%	—
Nov 5, 2025	BMO	-0.52	-0.46	+11.5%	35.08	-0.3%	-1.9%	-1.9%	-1.1%	+2.0%	+3.9%	—
Aug 11, 2025	BMO	-0.68	-0.41	+39.7%	20.03	-0.7%	+4.8%	+4.8%	+4.4%	+4.4%	+3.9%	—
May 12, 2025	BMO	-0.45	-0.62	-37.8%	12.90	-3.6%	-0.5%	-0.5%	-7.0%	+4.2%	+4.1%	—
Mar 20, 2025	BMO	-0.57	-3.38	-493.0%	13.88	-1.2%	-1.4%	-1.4%	-12.8%	-6.8%	-13.3%	—
Nov 27, 2024	BMO	—	-0.92	—	—	—	—	—	—	—	—	—

Date	Firm	Action	Grade	Target	Base	Open	Gap%	D1%	D2%	D3%	D4%	D5%
May 5	Wedbush	Initiates	Outperform	$53	$40.45	$41.53	+2.7%	+1.3%	+7.0%	+7.1%	+9.3%	—
Apr 28	Jones Trading	Maintains	Buy → Buy	—	$39.21	$39.68	+1.2%	+1.0%	-4.5%	-1.3%	-0.2%	+3.2%
Apr 27	BTIG	Maintains	Buy → Buy	—	$38.11	$38.02	-0.2%	+2.9%	+3.9%	-1.8%	+1.5%	+2.7%
Mar 3	Guggenheim	Maintains	Buy → Buy	—	$33.92	$33.92	+0.0%	+0.5%	+1.9%	+1.9%	+5.9%	+10.6%
Mar 2	BTIG	Maintains	Buy → Buy	—	$36.54	$32.89	-10.0%	-7.2%	-6.7%	-5.4%	-5.4%	-1.7%
Jan 14	BTIG	Maintains	Buy → Buy	—	$36.81	$36.89	+0.2%	+11.9%	+5.5%	+6.2%	+8.7%	+10.8%
Jan 7	BTIG	Maintains	Buy → Buy	—	$37.22	$38.14	+2.5%	+16.1%	-1.7%	+5.5%	-2.4%	-1.1%
Dec 1	RBC Capital	Downgrade	Sector Perform → Underperform	—	$43.57	$40.76	-6.4%	-10.6%	-10.5%	-5.5%	-6.2%	-7.5%

Data updated apr 27, 2026 1:21am · Source: massive.com