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Portfolio (Quarterly) Guide ↗

Siren, L.L.C.

· CIK 0002005245
13F Portfolio $4.9B AUM 119 positions Filed Aug 13, 2026 EDGAR ↗ ← All Funds
Q2 2026 · All 117 New
Page 4 of 6  ·  117 positions
# Ticker Company Sector Shares Value ↓ % Port Chg Shares Chg % Period Price ① Since Period ①
61 — Nebius Group NV — 52,000.0 $14.4M 0.29% NEW — $276.17 —
62 MSFT Microsoft Corp Technology 37,500.0 $14.0M 0.28% NEW — $373.02 +38.2%
63 CTMX CytomX Therapeutics Inc Healthcare 3,457,711.0 $13.0M 0.26% NEW — $3.75 -31.3%
64 GENB Generate Biomedicines Inc Financial Services 736,104.0 $12.4M 0.25% NEW — $16.87 -19.3%
65 — Inhibikase Therapeutics Inc — 5,850,000.0 $11.9M 0.24% NEW — $2.03 —
66 ADAG Adagene Inc Healthcare 2,666,666.0 $11.2M 0.23% NEW — $4.20 -31.7%
67 — enGene Therapeutics Inc — 6,256,662.0 $10.8M 0.22% NEW — $1.73 —
68 WHWK Whitehawk Therapeutics Inc Healthcare 2,337,102.0 $10.7M 0.22% NEW — $4.58 -18.8%
69 DDOG Datadog Inc Technology 40,000.0 $10.4M 0.21% NEW — $260.36 +6.9%
70 NOW ServiceNow Inc Technology 100,000.0 $9.9M 0.20% NEW — $99.28 +35.1%
71 AVGO Broadcom Inc Technology 25,000.0 $9.4M 0.19% NEW — $377.75 -5.8%
72 IONQ IONQ Inc Technology 170,000.0 $9.1M 0.18% NEW — $53.26 -18.5%
73 MSFT CALL Microsoft Corp Technology 24,000.0 $9.0M 0.18% NEW — $373.02 +38.2%
74 FROG Jfrog Ltd Technology 95,500.0 $8.7M 0.18% NEW — $90.88 +4.9%
75 — Oculis Holding AG — 625,000.0 $8.7M 0.17% NEW — $13.87 —
76 IREN IREN Ltd Financial Services 175,000.0 $8.0M 0.16% NEW — $45.73 -9.1%
77 AMZN Amazon.com Inc Consumer Cyclical 32,500.0 $7.7M 0.16% NEW — $238.34 +5.3%
78 CRWD CrowdStrike Holdings Inc Technology 10,000.0 $7.6M 0.15% NEW — $190.78 +41.3%
79 DSGN Design Therapeutics Inc Healthcare 523,212.0 $7.6M 0.15% NEW — $14.47 -14.2%
80 PDD PDD Holdings Inc Consumer Cyclical 95,000.0 $7.2M 0.15% NEW — $76.28 -1.3%
Page 4 of 6  ·  117 positions

① Period Price is the implied market price on the last day of the reporting period, calculated as reported value ÷ shares held. It is not the fund's purchase price or cost basis — the fund may have initiated or added to the position at any point during the quarter at a different price. Since Period shows the price change from that quarter-end snapshot to today's last price — it reflects stock movement after the report date, not the fund's actual return.

Sector Allocation
Healthcare 92.4%
Technology 3.9%
Communication Services 1.8%
Financial Services 1.3%
Consumer Cyclical 0.6%
Real Estate 0.0%