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Portfolio (Quarterly) Guide ↗

RTW INVESTMENTS, LP

· CIK 0001493215
13F Portfolio $10.0B AUM 88 positions Filed May 15, 2026 EDGAR ↗ ← All Funds
Q1 2026 Q4 2025 · All 9 New 25 Added 12 Reduced 12 Exited
Page 1 of 5  ·  88 positions
# Ticker Company Sector Shares Value ↓ % Port Chg Shares Chg % Period Price ① Since Period ①
1 MDGL MADRIGAL PHARMACEUTICALS INC Healthcare 1,993,687.0 $1.04B 10.38% $523.47 +3.1%
2 INSM INSMED INC Healthcare 4,842,880.0 $791.9M 7.88% $163.52 -29.3%
3 PTGX PROTAGONIST THERAPEUTICS INC Healthcare 5,059,053.0 $533.2M 5.31% $105.40 +0.1%
4 PTCT PTC THERAPEUTICS INC Healthcare 7,746,415.0 $527.8M 5.25% $68.13 +6.7%
5 ARGX ARGENX SE Healthcare 709,446.0 $518.1M 5.16% +36K +5.3% $730.25 +9.5%
6 CGON CG ONCOLOGY INC Healthcare 6,984,808.0 $472.7M 4.70% +5.0M +247.1% $67.68 -1.1%
7 CELC CELCUITY INC Healthcare 3,039,621.0 $346.9M 3.45% +2.5M +452.5% $114.14 +20.6%
8 TNGX TANGO THERAPEUTICS INC Healthcare 13,300,620.0 $278.2M 2.77% +11.8M +791.9% $20.92 +18.9%
9 ERAS ERASCA INC Healthcare 16,157,175.0 $261.4M 2.60% +16.0M +10000.0% $16.18 -35.9%
10 NTRA NATERA INC Healthcare 1,250,000.0 $250.0M 2.49% -250K -16.7% $199.99 -1.5%
11 RDNT RADNET INC Healthcare 4,285,000.0 $239.5M 2.38% +346K +8.8% $55.89 -4.4%
12 TARS TARSUS PHARMACEUTICALS INC Healthcare 3,346,025.0 $234.7M 2.34% $70.15 -7.1%
13 APOGEE THERAPEUTICS INC 2,782,097.0 $234.2M 2.33% +70K +2.6% $84.17
14 SYRE SPYRE THERAPEUTICS INC Healthcare 4,171,996.0 $210.4M 2.09% $50.44 +50.0%
15 COGT COGENT BIOSCIENCES INC Healthcare 5,458,675.0 $210.1M 2.09% -2.1M -28.1% $38.49 -11.2%
16 IRTC IRHYTHM HOLDINGS INC Healthcare 1,668,500.0 $196.9M 1.96% +487K +41.2% $118.02 -3.3%
17 STOK STOKE THERAPEUTICS INC Healthcare 5,623,525.0 $183.1M 1.82% +77K +1.4% $32.56 -3.7%
18 CYTK CYTOKINETICS INC Healthcare 2,721,158.0 $179.4M 1.78% $65.91 +19.3%
19 ACAD ACADIA PHARMACEUTICALS INC Healthcare 7,144,524.0 $159.0M 1.58% $22.26 -3.9%
20 ESTA ESTABLISHMENT LABS HLDGS INC Healthcare 2,655,695.0 $150.8M 1.50% +67K +2.6% $56.78 +22.9%
Page 1 of 5  ·  88 positions

Period Price is the implied market price on the last day of the reporting period, calculated as reported value ÷ shares held. It is not the fund's purchase price or cost basis — the fund may have initiated or added to the position at any point during the quarter at a different price. Since Period shows the price change from that quarter-end snapshot to today's last price — it reflects stock movement after the report date, not the fund's actual return.

Sector Allocation
Healthcare 99.6%
Technology 0.4%