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Portfolio (Quarterly) Guide ↗

TWO SIGMA INVESTMENTS, LP

· CIK 0001179392
13F Portfolio $123.9B AUM 4,546 positions Filed May 15, 2026 EDGAR ↗ ← All Funds
Q1 2026 Q4 2025 · All 1074 New 2043 Added 1209 Reduced 569 Exited
Page 74 of 103  ·  2,043 positions
# Ticker Company Sector Shares Value ↓ % Port Chg Shares Chg % Period Price ① Since Period ①
1461 TECH BIO-TECHNE CORP Healthcare 66,100.0 $3.5M 0.00% +6K +9.6% $52.26 -13.0%
1462 ESRT EMPIRE ST RLTY TR INC Real Estate 662,963.0 $3.4M 0.00% +268K +67.7% $5.20 +4.6%
1463 MED MEDIFAST INC Consumer Cyclical 338,158.0 $3.4M 0.00% +258K +320.9% $10.19 +23.7%
1464 DIS PUT DISNEY WALT CO Communication Services 35,700.0 $3.4M 0.00% +13K +56.6% $96.38 +6.1%
1465 FMNB FARMERS NATIONAL BANC CORP Financial Services 260,336.0 $3.4M 0.00% +53K +25.6% $13.16 +5.8%
1466 VFMV VANGUARD WELLINGTON FD 25,700.0 $3.4M 0.00% +10K +68.0% $133.23 +5.3%
1467 ANIK ANIKA THERAPEUTICS INC Healthcare 236,120.0 $3.4M 0.00% +2K +1.0% $14.50 +4.4%
1468 MG MISTRAS GROUP INC Industrials 231,325.0 $3.4M 0.00% +98K +74.0% $14.78 +13.4%
1469 ALNT ALLIENT INC Technology 57,815.0 $3.4M 0.00% +30K +104.3% $59.09 +7.2%
1470 MSEX MIDDLESEX WTR CO Utilities 65,517.0 $3.4M 0.00% +61K +1498.0% $52.05 -2.1%
1471 LLY PUT ELI LILLY & CO Healthcare 3,700.0 $3.4M 0.00% +700.0 +23.3% $919.77 +11.1%
1472 NSSC NAPCO SEC TECHNOLOGIES INC Industrials 86,200.0 $3.4M 0.00% +60K +224.1% $39.39 -9.1%
1473 FLNA FILANA THERAPEUTICS INC Healthcare 1,988,814.0 $3.4M 0.00% +1.3M +209.6% $1.69 -26.0%
1474 CRBU CARIBOU BIOSCIENCES INC Healthcare 1,759,934.0 $3.3M 0.00% +740K +72.5% $1.90 +5.3%
1475 TDAY USA TODAY CO INC Communication Services 473,904.0 $3.3M 0.00% +124K +35.3% $7.05 +6.5%
1476 VOYA VOYA FINANCIAL INC Financial Services 48,900.0 $3.3M 0.00% +38K +339.0% $68.32 +17.1%
1477 SNOW CALL SNOWFLAKE INC Technology 22,000.0 $3.3M 0.00% +3K +15.8% $150.82 +12.4%
1478 GNW GENWORTH FINL INC Financial Services 408,600.0 $3.3M 0.00% +358K +705.6% $8.12 +12.8%
1479 TSHA TAYSHA GENE THERAPIES INC Healthcare 742,081.0 $3.3M 0.00% +391K +111.3% $4.47 +16.1%
1480 MRNA PUT MODERNA INC Healthcare 65,000.0 $3.3M 0.00% +56K +647.1% $50.80 -10.0%
Page 74 of 103  ·  2,043 positions

Period Price is the implied market price on the last day of the reporting period, calculated as reported value ÷ shares held. It is not the fund's purchase price or cost basis — the fund may have initiated or added to the position at any point during the quarter at a different price. Since Period shows the price change from that quarter-end snapshot to today's last price — it reflects stock movement after the report date, not the fund's actual return.

Sector Allocation
Technology 21.8%
Financial Services 15.2%
Healthcare 13.2%
Industrials 13.1%
Consumer Cyclical 11.6%
Energy 5.2%
Basic Materials 5.1%
Consumer Defensive 4.6%
Communication Services 4.0%
Real Estate 3.7%