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Holdings (Monthly) Guide ↗

Pharmaceuticals Ultrasector Profund

· ProFunds
Monthly Holdings $16M AUM 80 positions Period Jul 2026 Filed Sep 23, 2026 EDGAR ↗ ← All Funds
All 19 New 51 Added 4 Reduced 6 Exited · Jul 2026 vs Jan 2026
# Name Ticker Since Shares Shares Δ Value Val Δ% % Port Cat
1 N/A N/A Jan 2026 703,000 +602,000 $703K +596.0% 8.20% RA
2 N/A N/A Jan 2026 541,000 NEW $541K — 6.31% RA
3 N/A N/A Jan 2026 433,000 NEW $433K — 5.05% RA
4 N/A N/A Jan 2026 433,000 NEW $433K — 5.05% RA
5 N/A N/A Jan 2026 339,000 NEW $339K — 3.95% RA
6 CRINETICS PHARMACEUTICALS INC 22663K107 Jan 2026 2,675 +1,474 $223K +272.5% 2.60% EC
7 MBX BIOSCIENCES INC 55287L101 Jan 2026 2,963 +960 $195K +164.7% 2.28% EC
8 ATAIBECKLEY INC 04650F101 Jul 2026 24,288 NEW $174K — 2.03% EC
9 DEFINIUM THERAPEUTICS INC 24477V105 Jan 2026 3,950 -714 $172K +118.4% 2.00% EC
10 AMYLYX PHARMACEUTICALS INC 03237H101 Jan 2026 6,821 +2,457 $139K +122.1% 1.62% EC
11 ENLIVEN THERAPEUTICS INC 29337E102 Jan 2026 2,481 +303 $136K +136.0% 1.59% EC
12 CORCEPT THERAPEUTICS INC 218352102 Jan 2026 1,175 +498 $135K +398.4% 1.57% EC
13 ALUMIS INC 022307102 Jan 2026 4,577 +3,560 $129K +418.7% 1.51% EC
14 N/A N/A Jan 2026 128,000 NEW $128K — 1.49% RA
15 NUVATION BIO INC 67080N101 Jan 2026 20,045 +12,680 $127K +228.8% 1.48% EC
16 TREVI THERAPEUTICS INC 89532M101 Jan 2026 6,851 +2,776 $125K +193.1% 1.46% EC
17 LIQUIDIA CORP 53635D202 Jan 2026 1,407 -360 $118K +58.0% 1.38% EC
18 NEKTAR THERAPEUTICS 640268306 Jan 2026 1,617 +617 $114K +206.1% 1.33% EC
19 AMNEAL PHARMACEUTICALS INC 03168L105 Jan 2026 5,993 +1,264 $110K +69.7% 1.28% EC
20 BRISTOL-MYERS SQUIBB COMPANY 110122108 Jan 2026 1,651 +524 $108K +73.8% 1.26% EC
21 EDGEWISE THERAPEUTICS INC 28036F105 Jan 2026 2,789 +357 $107K +56.6% 1.25% EC
22 OMEROS CORP 682143102 Jan 2026 9,001 +5,982 $107K +202.0% 1.24% EC
23 LIGAND PHARMACEUTICALS INC 53220K504 Jan 2026 370 +56 $106K +76.4% 1.24% EC
24 ELANCO ANIMAL HEALTH INC 28414H103 Jan 2026 4,014 +1,303 $106K +62.1% 1.23% EC
25 VERADERMICS INC 922967104 Jul 2026 987 NEW $104K — 1.21% EC
26 PACIRA BIOSCIENCES INC 695127100 Jan 2026 3,920 +1,627 $104K +119.8% 1.21% EC
27 VIATRIS INC 92556V106 Jan 2026 5,822 +845 $102K +56.9% 1.19% EC
28 JAZZ PHARMACEUTICALS PLC G50871105 Jan 2026 400 +50 $101K +75.7% 1.18% EC
29 ETON PHARMACEUTICALS INC 29772L108 Jul 2026 2,169 NEW $101K — 1.17% EC
30 MAZE THERAPEUTICS INC 578784100 Jan 2026 3,733 +2,438 $100K +78.1% 1.17% EC
31 MERCK & COMPANY INC 58933Y105 Jan 2026 771 +180 $100K +54.0% 1.17% EC
32 HARROW INC 415858109 Jan 2026 2,557 +1,407 $99K +110.6% 1.16% EC
33 JOHNSON & JOHNSON 478160104 Jan 2026 385 +105 $99K +55.1% 1.15% EC
34 ROYALTY PHARMA PLC G7709Q104 Jan 2026 1,684 +175 $98K +56.4% 1.15% EC
35 INDIVIOR PHARMACEUTICALS INC 45579U109 Jan 2026 2,410 +781 $96K +67.3% 1.12% EC
36 PRESTIGE CONSUMER HEALTHCARE INC 74112D101 Jan 2026 1,869 +928 $94K +54.7% 1.09% EC
37 COLLEGIUM PHARMACEUTICAL INC 19459J104 Jan 2026 2,638 +1,456 $93K +72.0% 1.09% EC
38 ELI LILLY & COMPANY 532457108 Jan 2026 81 +23 $93K +54.7% 1.08% EC
39 ORGANON & COMPANY 68622V106 Jan 2026 6,862 -1,180 $93K +35.4% 1.08% EC
40 EYEPOINT INC 30233G209 Jan 2026 7,446 +3,993 $91K +95.4% 1.06% EC
41 HARMONY BIOSCIENCES HOLDINGS INC 413197104 Jan 2026 2,588 +1,118 $91K +69.9% 1.06% EC
42 SUPERNUS PHARMACEUTICALS INC 868459108 Jan 2026 2,036 +785 $91K +50.8% 1.06% EC
43 PFIZER INC 717081103 Jan 2026 3,586 +1,346 $90K +51.4% 1.05% EC
44 WAVE LIFE SCIENCES LTD Y95308105 Jan 2026 16,221 +13,367 $89K +142.0% 1.04% EC
45 PHIBRO ANIMAL HEALTH CORP 71742Q106 Jan 2026 2,460 +1,117 $89K +65.7% 1.04% EC
46 ANI PHARMACEUTICALS INC 00182C103 Jan 2026 1,122 +418 $89K +54.3% 1.04% EC
47 TARSUS PHARMACEUTICALS INC 87650L103 Jan 2026 1,498 +788 $88K +93.0% 1.03% EC
48 ZOETIS INC 98978V103 Jan 2026 1,129 +640 $87K +43.0% 1.02% EC
49 OCULAR THERAPEUTIX INC 67576A100 Jan 2026 10,504 +6,754 $86K +150.4% 1.00% EC
50 XERIS BIOPHARMA HOLDINGS INC 98422E103 Jan 2026 10,572 +2,252 $85K +39.5% 1.00% EC
51 RAPPORT THERAPEUTICS INC 75383L102 Jan 2026 2,076 +150 $85K +66.0% 0.99% EC
52 INNOVIVA INC 45781M101 Jan 2026 3,992 +1,192 $84K +49.5% 0.98% EC
53 PERRIGO COMPANY PLC G97822103 Jan 2026 8,219 +3,948 $83K +36.9% 0.97% EC
54 AXSOME THERAPEUTICS INC 05464T104 Jan 2026 373 -14 $81K +14.0% 0.95% EC
55 AMPHASTAR PHARMACEUTICALS INC 03209R103 Jan 2026 3,730 +1,833 $74K +48.0% 0.87% EC
56 ARVINAS INC 04335A105 Jan 2026 9,028 +4,666 $72K +24.2% 0.85% EC
57 ALTO NEUROSCIENCE INC 02157Q109 Jul 2026 2,671 NEW $72K — 0.84% EC
58 SEPTERNA INC 81734D104 Jan 2026 1,779 +737 $61K +152.0% 0.71% EC
59 LB PHARMACEUTICALS INC 50180M108 Jul 2026 1,477 NEW $59K — 0.69% EC
60 CORMEDIX INC 21900C308 Jan 2026 7,721 +3,334 $58K +70.8% 0.68% EC
61 THERAVANCE BIOPHARMA INC G8807B106 Jan 2026 3,386 +1,977 $57K +113.9% 0.67% EC
62 ACLARIS THERAPEUTICS INC 00461U105 Jul 2026 10,166 NEW $53K — 0.62% EC
63 PHATHOM PHARMACEUTICALS INC 71722W107 Jan 2026 5,895 +2,474 $52K +10.3% 0.60% EC
64 ZEVRA THERAPEUTICS INC 488445206 Jan 2026 5,187 +1,255 $49K +39.4% 0.58% EC
65 RELMADA THERAPEUTICS INC 75955J402 Jul 2026 9,199 NEW $49K — 0.57% EC
66 AQUESTIVE THERAPEUTICS INC 03843E104 Jan 2026 11,061 +4,782 $41K +120.6% 0.48% EC
67 FULCRUM THERAPEUTICS INC 359616109 Jul 2026 11,341 NEW $41K — 0.47% EC
68 LEXICON PHARMACEUTICALS INC 528872302 Jul 2026 15,756 NEW $36K — 0.42% EC
69 BIOAGE LABS INC 09077V100 Jul 2026 3,681 NEW $33K — 0.39% EC
70 EVOLUS INC 30052C107 Jan 2026 4,569 +79 $27K +26.7% 0.31% EC
71 N/A N/A Jan 2026 -45 NEW $3K — 0.03% DE
72 N/A N/A Jan 2026 -13 NEW $-12 — -0.00% DE
73 N/A N/A Jan 2026 347 NEW $-20602 — -0.24% DE
74 N/A N/A Jan 2026 586 NEW $-49849 — -0.58% DE
✕ Avadel Pharmaceuticals PLC G29687103 — 2,688 SOLD $0.1M — — —
✕ Esperion Therapeutics Inc 29664W105 — 15,075 SOLD $0.1M — — —
✕ Ventyx Biosciences Inc. 92332V107 — 3,368 SOLD $0.0M — — —
✕ Terns Pharmaceuticals Inc. 880881107 — 1,294 SOLD $0.0M — — —
✕ AGPXX 825252885 — 34,370 SOLD $0.0M — — —
✕ Lenz Therapeutics Inc 52635N103 — 1,869 SOLD $0.0M — — —