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Portfolio (Quarterly) Guide ↗

TWO SIGMA INVESTMENTS, LP

· CIK 0001179392
13F Portfolio $123.9B AUM 4,546 positions Filed May 15, 2026 EDGAR ↗ ← All Funds
Q1 2026 Q4 2025 · All 1074 New 2043 Added 1209 Reduced 569 Exited
Page 209 of 228  ·  4,546 positions
# Ticker Company Sector Shares Value ↓ % Port Chg Shares Chg % Period Price ① Since Period ①
4161 ARWR PUT ARROWHEAD PHARMACEUTICALS IN Healthcare 4,100.0 $257K NEW $62.70 +16.7%
4162 LOANDEPOT INC 180,702.0 $257K -970K -84.3% $1.42
4163 JBIO JADE BIOSCIENCES INC Healthcare 18,251.0 $256K +2K +10.6% $14.05 +56.7%
4164 ERAS ERASCA INC Healthcare 15,800.0 $256K -22K -58.5% $16.18 -36.5%
4165 OBIO ORCHESTRA BIOMED HLDGS INC Healthcare 60,107.0 $255K -26K -30.6% $4.25 -6.4%
4166 BLDR PUT BUILDERS FIRSTSOURCE INC Industrials 3,100.0 $255K NEW $82.33 -19.4%
4167 VYNE THERAPEUTICS INC 426,412.0 $255K +206K +93.8% $0.60
4168 RGLD PUT ROYAL GOLD INC Basic Materials 1,000.0 $254K NEW $254.49 -11.1%
4169 HRTX HERON THERAPEUTICS INC Healthcare 317,400.0 $254K -682K -68.2% $0.80 +6.0%
4170 BLSH BULLISH Technology 7,100.0 $254K -12K -62.3% $35.73 +1.4%
4171 HVT HAVERTY FURNITURE COS INC Consumer Cyclical 11,939.0 $253K NEW $21.18 +0.0%
4172 SSYS STRATASYS LTD Technology 32,358.0 $253K +13K +69.2% $7.81 +5.4%
4173 CALL EXPAND ENERGY CORPORATION 2,300.0 $252K -9K -79.1% $109.78
4174 MOS PUT MOSAIC CO Basic Materials 9,900.0 $252K NEW $25.50 -16.0%
4175 TWLO CALL TWILIO INC Communication Services 2,000.0 $252K -7K -78.7% $125.82 +57.1%
4176 DXCM CALL DEXCOM INC Healthcare 4,000.0 $251K NEW $62.80 +3.6%
4177 VGT VANGUARD WORLD FD 360.0 $251K -117K -99.7% $697.72 -84.0%
4178 CTVA PUT CORTEVA INC Basic Materials 3,000.0 $251K NEW $83.71 -3.1%
4179 RTH VANECK ETF TRUST 1,000.0 $251K NEW $250.89 +5.3%
4180 TRGP CALL TARGA RES CORP Energy 1,000.0 $251K NEW $250.73 +9.6%
Page 209 of 228  ·  4,546 positions

Period Price is the implied market price on the last day of the reporting period, calculated as reported value ÷ shares held. It is not the fund's purchase price or cost basis — the fund may have initiated or added to the position at any point during the quarter at a different price. Since Period shows the price change from that quarter-end snapshot to today's last price — it reflects stock movement after the report date, not the fund's actual return.

Sector Allocation
Technology 21.8%
Financial Services 15.2%
Healthcare 13.2%
Industrials 13.1%
Consumer Cyclical 11.6%
Energy 5.2%
Basic Materials 5.1%
Consumer Defensive 4.6%
Communication Services 4.0%
Real Estate 3.7%