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Portfolio (Quarterly) Guide ↗

TWO SIGMA INVESTMENTS, LP

· CIK 0001179392
13F Portfolio $123.9B AUM 4,546 positions Filed May 15, 2026 EDGAR ↗ ← All Funds
Q1 2026 Q4 2025 · All 1074 New 2043 Added 1209 Reduced 569 Exited
Page 3 of 103  ·  2,043 positions
# Ticker Company Sector Shares Value ↓ % Port Chg Shares Chg % Period Price ① Since Period ①
41 ANET ARISTA NETWORKS INC Technology 3,758,279.0 $461.4M 0.37% +2.1M +130.5% $122.78 +15.6%
42 UNH UNITEDHEALTH GROUP INC Healthcare 1,700,196.0 $460.1M 0.37% +1.7M +6899.3% $270.59 +47.5%
43 META META PLATFORMS INC Communication Services 783,225.0 $448.1M 0.36% +774K +8506.9% $572.13 +8.1%
44 EQIX EQUINIX INC Real Estate 452,267.0 $443.3M 0.36% +179K +65.7% $980.24 +10.1%
45 GM GENERAL MTRS CO Consumer Cyclical 5,934,561.0 $442.1M 0.36% +2.6M +79.7% $74.50 +4.4%
46 IONS IONIS PHARMACEUTICALS INC Healthcare 5,857,629.0 $439.8M 0.35% +3.2M +120.3% $75.09 +3.3%
47 ABNB AIRBNB INC Consumer Cyclical 3,458,771.0 $436.8M 0.35% +1.5M +80.8% $126.28 +5.2%
48 ALB ALBEMARLE CORP Basic Materials 2,320,881.0 $416.7M 0.34% +1.1M +84.0% $179.53 +0.5%
49 HSY HERSHEY CO Consumer Defensive 1,975,205.0 $410.6M 0.33% +1.8M +958.8% $207.89 -8.5%
50 NBIX NEUROCRINE BIOSCIENCES INC Healthcare 3,060,570.0 $403.2M 0.33% +2.1M +210.8% $131.74 +20.7%
51 CTAS CINTAS CORP Industrials 2,359,681.0 $399.1M 0.32% +1.1M +93.8% $169.14 -1.9%
52 LNG CHENIERE ENERGY INC Energy 1,386,961.0 $393.6M 0.32% +782K +129.3% $283.76 -15.0%
53 HON HONEYWELL INTL INC Industrials 1,737,296.0 $392.7M 0.32% +1.2M +199.2% $226.03 -3.7%
54 GH GUARDANT HEALTH INC Healthcare 4,229,531.0 $390.7M 0.32% +2.1M +94.7% $92.37 +6.8%
55 VUG VANGUARD INDEX FDS 875,880.0 $382.6M 0.31% +59K +7.2% $436.79 -80.0%
56 ITW ILLINOIS TOOL WKS INC Industrials 1,468,075.0 $382.1M 0.31% +1.4M +1467.5% $260.29 -3.7%
57 QQQ INVESCO QQQ TR Financial Services 655,424.0 $378.3M 0.30% +132K +25.3% $577.18 +22.8%
58 SPY STATE STR SPDR S&P 500 ETF T Financial Services 580,293.0 $377.4M 0.30% +116K +25.0% $650.34 +13.7%
59 RSG REPUBLIC SVCS INC Industrials 1,709,115.0 $374.3M 0.30% +665K +63.7% $219.02 -4.7%
60 MPC MARATHON PETE CORP Energy 1,524,286.0 $372.2M 0.30% +637K +71.7% $244.18 +1.9%
Page 3 of 103  ·  2,043 positions

Period Price is the implied market price on the last day of the reporting period, calculated as reported value ÷ shares held. It is not the fund's purchase price or cost basis — the fund may have initiated or added to the position at any point during the quarter at a different price. Since Period shows the price change from that quarter-end snapshot to today's last price — it reflects stock movement after the report date, not the fund's actual return.

Sector Allocation
Technology 21.8%
Financial Services 15.2%
Healthcare 13.2%
Industrials 13.1%
Consumer Cyclical 11.6%
Energy 5.2%
Basic Materials 5.1%
Consumer Defensive 4.6%
Communication Services 4.0%
Real Estate 3.7%