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Portfolio (Quarterly) Guide ↗

TWO SIGMA INVESTMENTS, LP

· CIK 0001179392
13F Portfolio $123.9B AUM 4,546 positions Filed May 15, 2026 EDGAR ↗ ← All Funds
Q1 2026 Q4 2025 · All 1074 New 2043 Added 1209 Reduced 569 Exited
Page 102 of 103  ·  2,043 positions
# Ticker Company Sector Shares Value ↓ % Port Chg Shares Chg % Period Price ① Since Period ①
2021 CBUS CIBUS INC Healthcare 86,206.0 $171K +43K +97.4% $1.98 -33.8%
2022 YATSEN HLDG LTD 47,620.0 $147K +13K +39.4% $3.08
2023 WAFU WAH FU EDUCATION GROUP LIMIT Consumer Defensive 94,473.0 $146K +65K +216.0% $1.55 +12.6%
2024 LMRI LUMEXA IMAGING HOLDINGS INC Healthcare 16,894.0 $145K +3K +25.1% $8.60 -16.2%
2025 LONA LEONABIO INC Healthcare 13,276.0 $136K +3K +23.5% $10.28 +10.6%
2026 YEXT YEXT INC Technology 29,467.0 $113K +12K +67.2% $3.84 -7.6%
2027 HEPS D MARKET ELECTR SVCS & TRADI Consumer Cyclical 39,738.0 $104K +22K +121.5% $2.62 -1.1%
2028 ONKURE THERAPEUTICS INC 24,262.0 $100K +13K +114.3% $4.14
2029 INSE INSPIRED ENTMT INC Consumer Cyclical 13,452.0 $96K +400.0 +3.1% $7.13 +2.9%
2030 MYPS PLAYSTUDIOS INC Technology 181,100.0 $85K +152K +522.3% $0.47 +4.8%
2031 AQUABOUNTY TECHNOLOGIES INC 92,801.0 $80K +23K +33.0% $0.87
2032 QVCGA QVC GROUP INC Consumer Cyclical 28,864.0 $63K +4K +14.0% $2.17 -84.3%
2033 ORBS EIGHTCO HOLDINGS INC Technology 59,900.0 $56K +30K +99.3% $0.93 -4.5%
2034 BRIDGER AEROSPACE GRP HLDGS 23,524.0 $47K +200.0 +0.9% $1.98
2035 IMMP IMMUTEP LTD Healthcare 124,760.0 $44K +30K +31.9% $0.35 +48.1%
2036 BIOX BIOCERES CROP SOLUTIONS CORP Basic Materials 95,312.0 $42K +81K +572.1% $0.44 -3.6%
2037 PHIO PHARMACEUTICALS CORP 32,495.0 $40K +18K +124.2% $1.22
2038 JOB GEE GROUP INC Industrials 140,500.0 $34K +60K +74.1% $0.24 -0.0%
2039 HUIZE HLDG LTD 23,314.0 $28K +9K +58.5% $1.21
2040 HUDI HUADI INTERNATIONAL GRP CO L Basic Materials 13,305.0 $16K +1K +9.0% $1.24 +0.0%
Page 102 of 103  ·  2,043 positions

Period Price is the implied market price on the last day of the reporting period, calculated as reported value ÷ shares held. It is not the fund's purchase price or cost basis — the fund may have initiated or added to the position at any point during the quarter at a different price. Since Period shows the price change from that quarter-end snapshot to today's last price — it reflects stock movement after the report date, not the fund's actual return.

Sector Allocation
Technology 21.8%
Financial Services 15.2%
Healthcare 13.2%
Industrials 13.1%
Consumer Cyclical 11.6%
Energy 5.2%
Basic Materials 5.1%
Consumer Defensive 4.6%
Communication Services 4.0%
Real Estate 3.7%